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Yadernyy Antigen Proliferiruyushchikh Kletok

Yadernyy Antigen Proliferiruyushchikh Kletok


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About the Book

Sovremennye proteomnye tekhnologii vyyavili nalichie i vazhnuyu rol' mnogochislennykh belok-belkovykh vzaimodeystviy, tak nazyvaemogo interaktoma. Mekhanizmy ego funktsionirovaniya v bol'shoy stepeni opredelyayut zhiznennye protsessy vnutri kletki. Nekotorye belki imeyut osobuyu rol', otlichayutsya nalichiem bol'shogo kolichestva partnerov i yavlyayutsya ob"edinyayushchimi tsentrami (khabami) interaktoma. Odnim iz takikh khabov yavlyaetsya yadernyy antigen proliferiruyushchikh kletok (PCNA, proliferating cell nuclear antigen). Avtor monografii, analiziruya svoi i literaturnye dannye, opisyvaet mekhanizmy i stroit modeli funktsionirovaniya etogo belka. Obnaruzhennaya rol' PCNA kak koordinatora razlichnykh protsessov daet predstavlenie ne tol'ko ob otdel'no vzyatom belke, no i o fundamental'nykh aspektakh sistemnoy biologii, vzglyady na kotorye seychas tol'ko nachinayut formirovat'sya. Dan bogatyy fakticheskiy material i opisany raznoobraznye eksperimental'nye podkhody biokhimii i proteomiki. Kniga prednaznachena ne tol'ko dlya spetsialistov, no i dlya vsekh lyudey, interesuyushchikhsya dannoy oblast'yu. Mozhet sluzhit' khoroshim dopolnitel'nym uchebnikom dlya studentov, izuchayushchikh biokhimiyu, proteomiku i sistemnuyu biologiyu.


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Product Details
  • ISBN-13: 9783845416557
  • Publisher: Lap Lambert Academic Publishing
  • Binding: Paperback
  • Language: Russian
  • Returnable: N
  • Spine Width: 12 mm
  • Weight: 358 gr
  • ISBN-10: 3845416556
  • Publisher Date: 29 Jul 2011
  • Height: 229 mm
  • No of Pages: 204
  • Series Title: Russian
  • Sub Title: Koordinator Kletochnykh Funktsiy
  • Width: 152 mm


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