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Tipizzazione degli antigeni HLA-B7 e HLA-B27 dei leucociti umani negli adulti sani

Tipizzazione degli antigeni HLA-B7 e HLA-B27 dei leucociti umani negli adulti sani


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About the Book

Gli antigeni leucocitari umani sono proteine geneticamente ereditate presenti sulla superficie delle cellule del sistema immunitario. Le cellule del sistema immunitario riconoscono gli antigeni solo quando vengono presentati loro accanto a una molecola MHC. Tre tipi principali di HLA di classe I, ovvero HLA-A, HLA-B e HLA-C, sono espressi dalla maggior parte delle cellule umane. Le HLA di classe I sono coinvolte nella discriminazione e nella presentazione degli antigeni ai linfociti T. I linfociti T uccidono la cellula che lo presenta. I linfociti T distruggono le cellule infettate da virus, compreso l'HIV. Lo sviluppo di un vaccino per l'HIV potrebbe essere favorito da una completa comprensione di quei rari casi in cui alcuni individui infettati dall'HIV controllano la replicazione del virus. La maggior parte di questi controllori d'élite esprime gli alleli di istocompatibilità HLA-B57 o HLA-B27; questi alleli rimangono le associazioni più solide con le basse concentrazioni di virus nel plasma.


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Product Details
  • ISBN-13: 9786205585702
  • Publisher: KS Omniscriptum Publishing
  • Binding: Paperback
  • Language: Italian
  • Returnable: N
  • Weight: 145 gr
  • ISBN-10: 6205585707
  • Publisher Date: 18 Jan 2023
  • Height: 229 mm
  • No of Pages: 56
  • Spine Width: 3 mm
  • Width: 152 mm


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Tipizzazione degli antigeni HLA-B7 e HLA-B27 dei leucociti umani negli adulti sani
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Tipizzazione degli antigeni HLA-B7 e HLA-B27 dei leucociti umani negli adulti sani
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