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Sviluppo di microsfere di fibroina di seta caricate con isoniazide

Sviluppo di microsfere di fibroina di seta caricate con isoniazide


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About the Book

L'attuale indagine sperimentale è dedicata alla preparazione di microsfere di piccole dimensioni e buona sfericità con il metodo della separazione di fase, utilizzando l'isoniazide (INH) come farmaco modello. La fibroina di seta possiede qualità intrinseche uniche come la biodegradabilità, la biocompatibilità o le proprietà di rilascio e la capacità di carico di farmaci regolabile. La capacità di carico delle molecole di farmaco nelle sfere di seta dipende dalla loro carica e idrofobicità o da un profilo di rilascio alterato. Nel presente lavoro sono state preparate microsfere di fibroina di seta caricate con Isoniazid utilizzando il metodo della separazione di fase. Le microsfere sono state valutate mediante spettroscopia ultravioletta-visibile, spettroscopia infrarossa a trasformata di Fourier, efficienza di intrappolamento e studi di microscopia elettronica a scansione. Gli studi di microscopia elettronica a scansione hanno rivelato che le microsfere di fibroina di seta caricate con isoniazide erano sferiche. La relazione sperimentale ha rivelato un nuovo metodo di formulazione a base acquosa per la creazione di sfere di seta con forma o dimensione e sfera controllabili. Le microsfere di seta caricate con isoniazide possono fungere da nanoformulazione ideale con studi elaborati.


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Product Details
  • ISBN-13: 9786206934325
  • Publisher: KS Omniscriptum Publishing
  • Binding: Paperback
  • Language: Italian
  • Returnable: N
  • Weight: 186 gr
  • ISBN-10: 6206934322
  • Publisher Date: 11 Dec 2023
  • Height: 229 mm
  • No of Pages: 84
  • Spine Width: 5 mm
  • Width: 152 mm


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