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Structure and Function of Antibodies

Structure and Function of Antibodies


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International Edition


About the Book

This book provides a detailed description of all kinds of therapeutic antibodies including IgGs, IgAs, IgEs, and IgMs, bispecific antibodies, chimeric antigen receptor antibodies, and antibody fragments. Details about how each of these antibodies interact with their ligands, the immune system, and their targets are provided. Additionally, this book delves into the details of antibody, Fc, and variable chain structures, and how subtle changes in structure, charge, flexibility, post-translational modification, and the ability to bind to natural antibody ligands can result in a significant impact on antibody activity and functionality. Finally, the book explains the critical quality attributes of modern therapeutic antibodies and how to ensure that antibodies entering development have the best possible chance of success.


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Product Details
  • ISBN-13: 9783039438976
  • Publisher: Mdpi AG
  • Publisher Imprint: Mdpi AG
  • Height: 244 mm
  • No of Pages: 440
  • Spine Width: 33 mm
  • Width: 170 mm
  • ISBN-10: 3039438972
  • Publisher Date: 05 Feb 2021
  • Binding: Hardback
  • Language: English
  • Returnable: N
  • Weight: 1192 gr


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