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Ruolo di Wnt5a nell'effetto del cisplatino e aumento della selettività

Ruolo di Wnt5a nell'effetto del cisplatino e aumento della selettività


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About the Book

Il mio libro riguarda lo studio della molecola Wnt5a come molecola cancerogena. Spiegherò i suoi diversi percorsi nell'avvio del cancro. Il libro si concentrerà anche sulle modifiche necessarie che gli permettono di essere una molecola inefficace e che può portare selettivamente 4 molecole di cisplatino alle cellule tumorali. Ci sarà un confronto teorico tra l'uso di Wnt5a come molecola terapeutica e altri inibitori Wnt. Anche le azioni molecolari del cisplatino, gli effetti collaterali, la combinazione e i meccanismi di resistenza sono discussi in dettaglio. Inoltre, vengono spiegati i vantaggi del glicoside cisplatino rispetto al cisplatino (non glicosilato). Parleremo dei vantaggi molecolari dell'aggiunta di wnt5a modificato alla cisplastina, come wnt5a modificato aumenterà la potenza del cisplatino, ridurrà i suoi effetti collaterali e antagonizzerà diversi meccanismi di resistenza al cisplatino delle cellule tumorali. La parte finale del libro comporta la metodologia della sintesi biochimica di wnt5a-cisplatino modificato. Inoltre includerà come possiamo confrontare l'efficacia della molecola inventata al cisplatino e al cisplatino glicosilato.


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Product Details
  • ISBN-13: 9786204108377
  • Publisher: Edizioni Sapienza
  • ISBN-10: 6204108379
  • Publisher Date: 24 Sep 2021


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