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Name: RNA Vaccines
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ISBN: 9781493964796

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RNA Vaccines

(Hardback) | Released: 17 Dec 2016

By: Thomas Kramps (Author) , Knut Elbers (Author) | Publisher: Humana Press | Publisher Imprint: Humana Press

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About the Book

1. Introduction to RNA Vaccines

Thomas Kramps and Knut Elbers

Part I: Self-replicating RNA Vectors

2. Self-replicating RNA

Birke A. Tews and Gregor Meyers

3. Self-replicating RNA Vaccine Delivery to Dendritic Cells

Thomas Démoulins, Pavlos C. Englezou, Panagiota Milona, Nicolas Ruggli, Nicola Tirelli, Chantal Pichon, Cédric Sapet, Thomas Ebensen, Carlos A. Guzmán, and Kenneth C. McCullough

4. Plant Expression of Trans-encapsidated Viral Nanoparticle Vaccines with Animal RNA Replicons

Yiyang Zhou, Alison A. McCormick, and Christopher M. Kearney

Part II: Non-replicating mRNA Vectors

5. RNActive(R) Technology: Generation and Testing of Stable and Immunogenic mRNA Vaccines

Susanne Rauch, Johannes Lutz, Aleksandra Kowalczyk, Thomas Schlake, and Regina Heidenreich

6. Nucleoside Modified mRNA Vaccines for Infectious Diseases

Norbert Pardi and Drew Weissman

7. Generation and Evaluation of Prophylactic mRNA Vaccines against Allergy

Richard Weiss, Sandra Scheiblhofer, and Josef Thalhamer

Part III: Adjuvantation and Delivery

8. Measuring the Adjuvant Activity of RNA Vaccines

Norbert Pardi and Drew Weissman

9. Generation of Immunostimulating 130 nm Protamine-RNA Nanoparticles

Marina Tusup and Steve Pascolo

10. Electroporation of mRNA as Universal Technology Platform to Transfect a Variety of Primary Cells with Antigens and Functional Proteins

Kerstin F. Gerer, Stefanie Hoyer, Jan Dörrie, and Niels Schaft

11. Adjuvant-Enhanced mRNA Vaccines

Lukasz Bialkowski, Kevin Van der Jeught, Dries Renmans, Alexia van Weijnen, Carlo Heirman, Marleen Keyaerts, Karine Breckpot, and Kris Thielemans

12. Enhanced Delivery of DNA or RNA Vaccines by Electroporation

Kate E. Broderick and Laurent M. Humeau

Part IV: Preclinical and Clinical Development

13. The European Regulatory Environment of RNA-Based Vaccines

Thomas Hinz, Kajo Kallen, Cedrik M. Britten, Bruno Flamion, Ulrich Granzer, Axel Hoos, Christoph Huber, Samir Khleif, Sebastian Kreiter, Hans-Georg Rammensee, Ugur Sahin, Harpreet Singh-Jasuja, Özlem Türeci, and Ulrich Kalinke

14. Discovery and Subtyping of Neo-Epitope Specific T-cell Responses for Cancer Immunotherapy: Addressing the Mutanome

Mustafa Diken, Mathias Vormehr, Christian Grunwitz, Sebastian Kreiter, Özlem Türeci, and Ugur Sahin

15. Considerations for Producing mRNA Vaccines for Clinical Trials

Andreas Schmid

16. Nonclinical Safety Testing of RNA Vaccines

Gundel Hager

17. Immunotherapy of Uveal Melanoma: Vaccination Against Cancer

Mirko Kummer and Beatrice Schuler-Thurner

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Product Details

ISBN-13: 9781493964796
Publisher: Humana Press
Publisher Imprint: Humana Press
Edition: 1st ed. 2017
Language: English
Returnable: Y
Spine Width: 18 mm
Weight: 779 gr

ISBN-10: 1493964798
Publisher Date: 17 Dec 2016
Binding: Hardback
Height: 254 mm
No of Pages: 282
Series Title: Methods in Molecular Biology
Sub Title: Methods and Protocols
Width: 178 mm

Related Categories

Medicine > Clinical & internal medicine > Cardiovascular medicine

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