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Name: RNA Interference
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ISBN: 9781493948918

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RNA Interference

(Paperback) | Released: 22 Sep 2016

By: Mouldy Sioud (Author) | Publisher: Humana Press | Publisher Imprint: Humana Press

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About the Book

1. RNA Interference: Mechanisms, Technical Challenges, and Therapeutic Opportunities

Mouldy Sioud

2. Nanostructured RNAs for RNA Interference

Yuko Nakashima, Naoko Abe, Yoshihiro Ito, and Hiroshi Abe

3. One Long Oligonucleotide or Two Short Oligonucleotides Based shRNA Construction and Expression

Xue-jun Wang and Sheng-qi Wang

4. PLGA Microspheres Encapsulating siRNA

Giuseppe De Rosa and Giuseppina Salzano

5. Magnetic Nanoparticle and Magnetic Field Assisted siRNA Delivery In Vitro

Olga Mykhaylyk, Yolanda Sanchez-Antequera, Dialechti Vlaskou, Maria Belen Cerda, Mehrdad Bokharaei, Edelburga Hammerschmid, Martina Anton, and Christian Plank

6. Cytoplasmic Delivery of siRNAs to Monocytes and Dendritic Cells Via Electroporation

Mouldy Sioud

7. Delivery of siRNAs to Cancer Cells Via Bacteria

Omar Ahmed, Andrea Krühn, and Hermann Lage

8. Microwell Array-Mediated Delivery of Lipoplexes Containing Nucleic Acids for Enhanced Therapeutic Efficacy

Yun Wu, Daniel Gallego-Perez, and L. James Lee

9. Modulating the Tumor Microenvironment with RNA Interference as a Cancer Treatment Strategy

Karin Zins, Mouldy Sioud, Seyedhossein Aharinejad, Trevor Lucas, and Dietmar Abraham

10. Targeted In Vivo Delivery of siRNA and an Endosome-Releasing Agent to Hepatocytes

Magdolna G. Sebestyén, So C. Wong, Vladimir Trubetskoy, David L. Lewis, and Christine I. Wooddell

11. Cell-Internalization SELEX: Method for Identifying Cell-Internalizing RNA Aptamers for Delivering siRNAs to Target Cells

William H. Thiel, Kristina W. Thiel, Katie S. Flenker, Tom Bair, Adam J. Dupuy, James O. McNamara II, Francis J. Miller, and Paloma H. Giangrande

12. Strategies for siRNA Navigation to Desired Cells

Mouldy Sioud

13. Analysis of RNA Interference-Mediated Hepatic Gene Silencing Following Murine Hydrodynamic Injection of Guanidinopropyl-Modified siRNAs

Maximilian C.R. Buffb, Stefan Bernhardt, Musa D. Marimani, Abdullah Ely, Joachim W. Engels, and Patrick Arbuthnot

14. Therapy of Respiratory Viral Infections with Intranasal siRNAs

Sailen Barik and Patrick Lu

15. Engineering Therapeutic Cancer Vaccines that Activate Anti-Tumor Immunity

Per Ole Iversen and Mouldy Sioud

16. Immunosuppressive Factor Blockade in Dendritic Cells Via siRNAs Results in Objective Clinical Responses

Mouldy Sioud, Anne Mobergslien, and Stein Sæbøe-Larssen

17. Targeting bcr-abl Transcripts with siRNAs in an Imatinib-Resistant Chronic Myeloid Leukemia Patient: Challenges and Future Directions

Michael Koldehoff

18. A Facile Method for Interfering with Off-Target Silencing Mediated by the Sense Strand

Anne Mobergslien and Mouldy Sioud

19. Overcoming the Challenges of siRNA Activation of Innate Immunity: Design Better Therapeutic siRNAs

Mouldy Sioud

20. Gene Silencing In Vitro and In Vivo Using Intronic MicroRNAs

Jia Han Deng, Peter Deng, Shi-Lung Lin, and Shao-Yao Ying

21. In Silico Identification of Novel Endo-siRNAs

Andrew Schuster, Grant W Hennig, Nicole Ortogero, Dickson Luong, and Wei Yan

22. Computer-Assisted Annotation of Small RNA Transcriptomes

Nicole Ortogero, Grant W. Hennig, Dickson Luong, and Wei Yan

23. miR-CATCH: MicroRNA Capture Affinity Technology

Sebastian Vencken, Tidi Hassan, Noel G. McElvaney, Stephen G.J. Smith, and Catherine M. Greene

24. Roles of

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Product Details

ISBN-13: 9781493948918
Publisher: Humana Press
Publisher Imprint: Humana Press
Edition: Softcover reprint of the original 1st ed. 2015
Language: English
Returnable: Y
Spine Width: 26 mm
Weight: 929 gr

ISBN-10: 1493948911
Publisher Date: 22 Sep 2016
Binding: Paperback
Height: 254 mm
No of Pages: 495
Series Title: Methods in Molecular Biology
Sub Title: Challenges and Therapeutic Opportunities
Width: 178 mm

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