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Resistance to Aromatase Inhibitors in Breast Cancer

Resistance to Aromatase Inhibitors in Breast Cancer


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International Edition


About the Book

.-1 Clinical Use of Aromatase Inhibitors in Breast Cancer: History and Present

.-2 Structure, Regulation and Polymorphisms of the Aromatase Gene

.-3 Structure, Function and Inhibition of Aromatase

.-4 In Vivo Models of AI Resistance

.-5 Ineffective inhibition of aromatase: a cause for AI resistance?

.-6 Understanding the New Biology of Estrogen-Induced Apoptosis and its Application in Patient Care

.-7 Ligand-independent signalling through estrogen receptor pathways in breast cancer

.-8 Chromatin and epigenetic determinants of resistance to aromatase inhibitors

.-9 Aromatase Inhibitor Resistance via Non-endocrine Signalling Pathways

.-10 Prediction of Response to Aromatase Inhibitors in Breast Cancer

.-11 Clinical Trials Combining Aromatase Inhibitors with Other Targeted Treatments

.-12 Aromatase Inhibitors Beyond Breast Cancer: Endometrium vs Breast Puzzle and Other Issues


About the Author: Alexey Larionov, Ph.D. is a researcher at the Academic Laboratory of Medical Genetics and Statistics and Computational Biology Lab at the University of Cambridge. Dr Larionov is an expert in endocrine resistance in breast cancer, as well as whole exome sequencing data analysis. Dr. Larionov has received over 1019 citations.


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Product Details
  • ISBN-13: 9783319382845
  • Publisher: Springer
  • Publisher Imprint: Springer
  • Edition: Softcover reprint of the original 1st ed. 2015
  • Language: English
  • Returnable: Y
  • Spine Width: 16 mm
  • Width: 156 mm
  • ISBN-10: 3319382845
  • Publisher Date: 17 Oct 2016
  • Binding: Paperback
  • Height: 234 mm
  • No of Pages: 288
  • Series Title: Resistance to Targeted Anti-Cancer Therapeutics
  • Weight: 480 gr


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Resistance to Aromatase Inhibitors in Breast Cancer
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Resistance to Aromatase Inhibitors in Breast Cancer
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