Part I: Overview of the Animal Research in Psychiatric Illness and Substance Abuse

1. New Frontiers in Animal Research of Psychiatric Illness

Arie Kaffman and John J. Krystal

2. Experimental Psychiatric Illness and Drug Abuse Models: From Human to Animal, An Overview

Scott Edwards and George F. Koob

3. Qualitative Vs. Quantitative Methods in Psychiatric Research

Mahdi Razafsha, Hura Behforuzi, Hassan Azari, Zhiqun Zhang, Kevin K. Wang, Firas H. Kobeissy, and Mark S. Gold

Part II: Methods in Animal Models of Psychiatric Illness

4. Animal Models of Self-Injurious Behavior: An Overview

Darragh P. Devine

5. Rodent Models of Adaptive Decision Making

Alicia Izquierdo and Annabelle M. Belcher

6. Animal Models of Depression and Neuroplasticity: Assessing Drug Action in Relation to Behavior and Neurogenesis

Ying Xu, Philip A. Barish, Jianchun Pan, William O. Ogle, and James M. O'Donnell

7. Modeling Depression in Animal Models

David H. Overstreet

8. Behavioral Model for Assessing Cognitive Decline

Michael Guidi and Thomas C. Foster

9. The Pemoline Model of Self-Injurious Behavior

Darragh P. Devine

10. Modeling Risky Decision Making in Rodents

Nicholas W. Simon and Barry Setlow

11. Modeling Open Space Anxiety Test in Rodents: The Elevated Platform with Steep Slopes

Abdelkader Ennaceur

12. An Animal Model to Study the Molecular Basis of Tardive Dyskinesia

Mahendra Bishnoi and Ravneet K. Boparai

Part III: Methods in Animal Models of Substance Abuse

13. Models of Chronic Alcohol Exposure and Dependence

Darin J. Knapp and George R. Breese

14. Rat Models of Prenatal and Adolescent Cannabis Exposure

Jennifer A. DiNieri and Yasmin L. Hurd

15. Modeling Nicotine Addiction in Rats

Stephanie Caille, Kelly Clemens, Luis Stinus, and Martine Cador

16. Animal Models of Nicotine Withdrawal: Intracranial Self-Stimulation and Somatic Signs of Withdrawal

Rayna M. Bauzo and Adrie W. Bruijnzeel

17. Methods in Drug Abuse Models: Comparison of Different Models of Methamphetamine Paradigms

Firas H. Kobeissy, Jeremiah D. Mitzelfelt, Irina Fishman, Drake Morgan, Roger Gaskins, Zhiqun Zhang, Mark S Gold, and Kevin Wang

18. Cocaine Self-Administration in Rats: Hold Down Procedures

Benjamin A. Zimmer and David C.S. Roberts

19. Cocaine Self-Administration in Rats: Discrete Trials Procedures

Carson V. Dobrin and David C.S. Roberts

20. Cocaine Self-Administration in Rats: Threshold Procedures

Erik B. Oleson and David C.S. Roberts

21. Assessing Locomotor-Stimulating Effects of Cocaine in Rodents

Drake Morgan, Jameson P. DuPree, Alex D. Bibbey, and Glen M. Sizemore

22. Methods in Tobacco Abuse: Proteomic Changes Following Second-Hand Smoke Exposure

Joy Guingab-Cagmat, Rayna M. Bauzo, Adrie W. Bruijnzeel, Kevin Wang, Mark S. Gold, and Firas H. Kobeissy

Part IV: Methods in Animal Models of Eating Disorders

23. Animal Models of Sugar and Fat Bingeing: Relationship to Food Addiction and Increased Body Weight