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Proteins of the Nucleolus

Proteins of the Nucleolus


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About the Book

Part I Introduction.- Chapter 1 Proteins of the nucleolus: An introduction.- 1.1 Introduction.- 1.2 Functional consequences of nuclear and nucleolar architecture (Chapter 2).- 1.3 rDNA and nucleologenesis in Drosophila (Chapter 3).- 1.4 The nucleolus of Dictyostelium and other lower eukaryotes (Chapter 4).- 1.5 Human rDNA genes: Identification of four fractions, their functions and nucleolar location (Chapter 5).- 1.6 Chromatin organization and the mammalian nucleolus (Chapter 6).- 1.7 Chaperones and multitasking proteins in the nucleolus (Chapter 7).- 1.8 Nucleolar localization/retention signals (Chapter 8).- 1.9 Nucleolar transport of putative GTPase GNL1 and related proteins (Chapter 9).- 1.10 Nucleolar protein anchoring and translocation (Chapter 10).- 1.11 The nucleolus as a stress response organelle (Chapter 11).- 1.12 The nucleolar aspect of breast cancer (Chapter 12).- 1.13 Cysteine proteinase inhibitors in the nucleus and nucleolus in activated macrophages (Chapter 13).- 1.14 Nucleolar proteins and cancer: The roles of Aurora A-interacting nucleolar proteins in mitosis and cancer (Chapter 14).- 1.15 Nucleolar transplantation and human embryogenesis (Chapter 15).- 1.16Conclusion.- Part II The nucleolus and nucleolar proteins.- Chapter 2 Functional consequences of nuclear and nucleolar architecture.- 2.1 General aspects of nuclear architecture.- 2.2 Nuclear architecture and epigenetic events during replication.- 2.3 General function and structure of nucleoli.- 2.4 Conclusions and future directions.- 2.5 Acknowledgements.- 2.6 Abbreviations.- 2.7 References.- Chapter 3 rDNA and nucleologenesis in Drosophila.- 3.1 Introduction.- 3.2 Nucleolar organizers contain rDNA genes.- 3.3 The Drosophila rDNA repeat unit.- 3.4 X-Y chromosome pairing in male meiosis is mediated by the 240bp IGS repeat.- 3.5 Growth-related expression of Drosophila rDNA.- 3.6 Centric heterochromatin flanking the NORs.- 3.7 Endo-replication of Drosophila rDNA.- 3.8 The bobbed mutation and rDNA magnification.- 3.9 rDNA compensation.- 3.10 Early work on R1 and R2 retrotransposons.- 3.11 Drosophila rDNA and epigenetic effects.- 3.12 Nucleologenesis in Drosophila melanogaster.- 3.13 Future endeavors.- 3.14 Acknowledgements.- 3.15 Abbreviations.- 3.16 References.- Chapter 4 The nucleolus of Dictyostelium and other lower eukaryotes.- 4.1 The nucleolus of Dictyostelium.- 4.1.1 Dictyostelium nucleolar structure during growth.- 4.2 Nucleolar proteins in Dictyostelium.- 4.3 The nucleolus in other lower eukaryotes.- 4.4 Conclusions.- 4.5 References.- Chapter 5 Human rDNA genes: Identification of four fractions, their functions and nucleolar location.- 5.1 Introduction.- 5.2 The rDNA copy number in the human genome.- 5.3 Four rDNA fractions, which differ in their structure, location, and functional activity.- 5.4 Phenotypical manifestations of genomic dose of active rRNA gene copies.- 5.5 References.- Chapter 6 Chromatin organization and the mammalian nucleolus.- 6.1 Genome organization principles and nuclear architecture.- 6.2 Organization of rRNA genes in the mammalian nucleolus.- 6.3 Chromosomal constitution of the human nucleolus-associated DNA.- 6.4 Epigenomics of the nucleolus from the proteomics perspective.- 6.5 Concluding remarks.- 6.6 References.- Chapter 7 Chaperones and multitasking proteins in the nucleolus.- 7.1 Nucleolar organization, chaperones and multitasking proteins.- 7.2 Analysis of nucleolar components and functions: New quantitative tools to measure proteins and transcription in the nucleolus.- 7.3 Targeting chaperones to the nucleolus.- 7.4 Nucleolar multitasking proteins (NoMPs).- 7.5 Links between conventional chaperones and NoMPs, possible roles for chaperones in the nucleolus.- 7.6 Open questions and future directions.- 7.7 List of abbreviations.- 7.8 References.- Part III Nucleolar protein translocation.- Chapter 8 Nucleolar localization


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Product Details
  • ISBN-13: 9789400797185
  • Publisher: Springer
  • Publisher Imprint: Springer
  • Edition: 2013 ed.
  • Language: English
  • Returnable: N
  • Spine Width: 20 mm
  • Weight: 580 gr
  • ISBN-10: 9400797184
  • Publisher Date: 12 Apr 2015
  • Binding: Paperback
  • Height: 234 mm
  • No of Pages: 371
  • Series Title: English
  • Sub Title: Regulation, Translocation, & Biomedical Functions
  • Width: 156 mm


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