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Nuclear Signaling Pathways and Targeting Transcription in Cancer

Nuclear Signaling Pathways and Targeting Transcription in Cancer


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About the Book

Preface.- Steroid Receptor Coactivators (SRCs) as Integrators of Multiple Signaling Pathways in Cancer Progression.- Role of Alteration/Deficiency in Activation (ADA) Complex in the Cell Cycle, Genomic Instability and Cancer.- RUNX2 Transcriptional Regulation in Development and Disease.- Epigenetic Mechanisms of Cancer Metastasis.- Regulatory Effects of Arsenic on Cellular Signaling Pathways: Biological Effects and Therapeutic Implications.- Nuclear Factors Linking Cancer and Inflammation.- Regulation of the Jak/STATs Pathways by Histone Deacetylases.- Receptor Tyrosine Kinases in the Nucleus: Nuclear Functions and Therapeutic Implications in Cancers.- Nucleolar Signaling Determines Cell Fate - The RP-Mdm2-p53 Axis Fine-Tunes Cellular Homeostasis.- Transcriptional Regulation of Lipogenesis as a Therapeutic Target for Cancer Treatment.- Selective Inhibition of Acetyl-Lysine Effector Domains of the Bromodomain Family in Oncology.- Domain Specific Targeting of Cancer.- The Potential of Targeting Splicing for Cancer Therapy.- Exploiting Cell Cycle Pathways in Cancer Therapy: New (and Old) Targets and Potential Strategies.- Histone Demethylases in Prostate Cancer.- Therapeutic Significance of Chromatin Remodeling Complexes in Cancer.- Index.


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Product Details
  • ISBN-13: 9781493901128
  • Publisher: Humana Press
  • Publisher Imprint: Humana Press
  • Edition: Softcover reprint of the original 1st ed. 2014
  • Language: English
  • Returnable: N
  • Spine Width: 23 mm
  • Width: 156 mm
  • ISBN-10: 1493901125
  • Publisher Date: 23 Aug 2015
  • Binding: Paperback
  • Height: 234 mm
  • No of Pages: 439
  • Series Title: Cancer Drug Discovery & Development
  • Weight: 680 gr


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Nuclear Signaling Pathways and Targeting Transcription in Cancer
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Nuclear Signaling Pathways and Targeting Transcription in Cancer
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