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Nitric Oxide and Cancer: Pathogenesis and Therapy

Nitric Oxide and Cancer: Pathogenesis and Therapy


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About the Book

Part I: Molecular Cell Signaling by NO in cancer
1. Inflammation-associated Carcinogenesis Involved Interaction Between with iNOS/NO and WNT/beta-catenin
Qiang Du and David A. Geller

2. NO and Genomic Stability
Vasily A. Yakovlev

3. Targeting Hyponitroxia in Cancer Therapy
Bryan Oronsky, Neil Oronsky, Michelle Lybeck, Gary Fanger, Jan Scicinski

4. Mechanism of NO-dependent Regulation of Invasion and Metastasis
Aideen E Ryan, Amy J Burke, Francis J Giles, Francis J Sullivan, Sharon A Glynn

5. NO Role in Protumorigenesis and Hypoxia
Lynne-Marie Postovit

Part II: S-nitrosylation and cancer
6. Impacts of S-nitrosylation in Cancer
Tysha N. Medeiros, Dana M. Jarigese, Melissa A. Edwards and
Mark A. Brown

7. S-nitrosylation of Cancer Cells
Ali Bettaieb, Stéphanie Plenchette, Catherine Paul, Véronique Laurens, Sabrina Romagny, Jean-François Jeannin

8. Role of S-nitrosylation in Cancer Metastasis
Sudjit Luanpitpong and Yon Rojanasakul

Part III: Modulation of anti-tumor immune responses by NO
9. NO Immunity and Cancer
Hermes J. Garbán

10. Regulation of Anti-tumor Responses by NO
Peter Siesjö

11. NO Immune Modulation and Tumor Growth
Naveena B. Janakiram and Chinthalapally V. Rao

Part IV: Therapeutics and overcoming resistance
12. Role of NO in Chemo-immune Resistance
Benjamin Bonavida

13. Emerging Role of NO-mediated Therapeutics
Cian M. McCrudden and Helen O. McCarthy
14. PDT and NO
Emilia Della Pietra and Valentina Rapozzi

15. Regulation of Cell Death by NO
Jordi Muntané, Francisco Gallardo-Chamizo, Sheila Pereira, Ángela M. De los Santos, Ángeles Rodríguez-Hernández, Luís M. Marín, Jose M. Álamo, Francisco J Padillo

16. Discovery and Development of RRx-001
Jan Scicinski, Bryan Oronsky, Shoucheng Ning, Gary R Fanger, Susan J Knox, Mark Bednarski

Part V: NO Meditated Alterations in Gene Products
17. Nitric Oxide Coagulation and Cancer
Benjamin A. Derman, Hau C. Kwaan, Malak Elbatarny, Maha Othman

18. Neutrosphyngomyelinase 2
Bei Lei Sun and Bulent Mutus


About the Author: Dr. Benjamin Bonavida is a professor at UCLA's David Geffen School of Medicine for the Department of Microbiology, Immunology, & Molecular Genetics. His other appointments include being a member of the Department of Defense Congressionally Directed Medical Research Program, Member of the National Cancer Institute's SPORE Program, member of the International Scientific Advisory Board of the Israel Cancer Research Foundation, to name a few. He's currently a scientific reviewer for several journals and a member of editorial boards including Journal of Clinical Immunology, International Journal of Oncology, and Cancer Biotherapy & Radiopharmaceuticals.


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Product Details
  • ISBN-13: 9783319136103
  • Publisher: Springer
  • Publisher Imprint: Springer
  • Depth: 25
  • Language: English
  • Returnable: Y
  • Spine Width: 21 mm
  • Weight: 702 gr
  • ISBN-10: 3319136100
  • Publisher Date: 01 Jun 2015
  • Binding: Hardback
  • Height: 234 mm
  • No of Pages: 308
  • Series Title: English
  • Sub Title: Pathogenesis and Therapy
  • Width: 156 mm


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