1. Introduction to the Immune System
Scott McComb, Aude Thiriot, Lakshmi Krishnan, and Felicity Stark
2. Immunoproteomics: Current Technology and Applications
Kelly M. Fulton and Susan M. Twine
3. Antigen Identification Using SEREX
Ugur Sahin and Özlem Türeci
4. Antigen Discovery Using Whole-Genome Phage Display Libraries
Elisa Beghetto and Nicola Gargano
5. Methods and Applications of Serological Proteome Analysis
Kelly M. Fulton, Shannon S. Martin, Lawrence Wolfraim, and Susan M. Twine
6. Pre-Absorbed Immunoproteomics: A Novel Method for the Detection of Bacterial Surface Proteins
Guangjin Liu, Wei Zhang, and Chengping Lu
7. Identification of the Antigen Content of Electroimmunoprecipitates
N. Helena Beyer and Niels H.H. Heegaard
8. An Immunoproteomics Approach to Screen the Antigenicity of the Influenza Virus
Kevin M. Downard
9. In Vivo Microbial Antigen Discovery (InMAD) to Identify Diagnostic Proteins and Polysaccharides that Are Circulating During Microbial Infections
Sindy J. Chaves, Kathleen Schegg, Thomas R. Kozel, and David P. AuCoin
10. Chemo-Enzymatic Production of O-Glycopeptides for the Detection of Serum Glycopeptide Antibodies
Alexander Nøstdal and Hans H. Wandall
11. Enrichment and Characterization of Glycopeptide Epitopes from Complex Mixtures
Luc Tessier, Kelly M. Fulton, and Susan M. Twine
12. Whole-Cell MALDI-TOF Mass Spectrometry: A Tool for Immune Cell Analysis and Characterization
Richard Ouedraogo, Julien Textoris, Aurélie Daumas, Christian Capo, and Jean-Louis Mege
13. Cell-Based Arrays for the Identification of Interacting Polypeptide Domains or Epitopes
Richard H. Maier, Christina J. Maier, and Kamil Önder
14. Identification and Quantitation of MHC Class II-Bound Peptides from Mouse Spleen Dendritic Cells by Immunoprecipitation and Mass Spectrometry Analysis
Leonia Bozzacco and Haiqiang Yu
15. Construction and Screening of an Antigen-Derived Peptide Library Displayed on Yeast Cell Surface for CD4+ T Cell Epitope Identification
Fei Wen and Huimin Zhao
16. Profiling of Cytokine and Chemokine Responses Using Multiplex Bead Array Technology
Greg Harris and Wangxue Chen
17. Preparation of the Low Molecular Weight Serum Proteome for Mass Spectrometry Analysis
Timothy J. Waybright, King C. Chan, Timothy D. Veenstra, and Zhen Xiao
18. Identification of Protein Biomarkers in Human Serum Using iTRAQ and Shotgun Mass Spectrometry
Theodoros A. Koutroukides, Julian A.J. Jaros, Bob Amess, Daniel Martins-de-Souza, Paul C. Guest, Hassan Rahmoune, Yishai Levin, Mike Deery, Philip D. Charles, Svenja Hester, Arnoud Groen, Andy Christoforou, Julie Howard, Nick Bond, Sabine Bahn, and Kathryn S. Lilley
19. Genome-Based Bioinformatic Prediction of Major Histocompatibility Complex (MHC) Epitopes
Simon J. Foote
20. Structure-Based Prediction of Major Histocompatibility Complex (MHC) Epitopes
Andrew J. Bordner
21. Prioritization of Therapeutic Targets of Inflammation Using Proteomics, Bioinformatics, and In Silico Cell-Cell Interactomics
Arsalan S. Haqqani and Danica B. Stanimirovic
22. Commercial Considerations for Immunoproteomics
Scott M. Ferguson