CHAPTER 1: Introduction John Saxton and Amanda Daley 1.1 Abstract 1.2 The burden of cancer 1.3 Stages of the cancer experience 1.4 Exercise and the cancer survivor 1.4.1 Cancer as a 'Teachable moment' 1.4.2 Health benefits of exercise 1.4.3 Exercise terminology 1.4.4 Exercise guidelines for cancer survivors 1.5 Levels of evidence 1.5.1 General overview 1.5.2 Observational studies 1.5.3 Qualitative studies 1.5.4 Randomized controlled trials 1.6 Dose-response issues 1.7 Aims of this book 1.8 References CHAPTER 2: Exercise and cancer-related fatigue syndrome Margaret L McNeely and Kerry S Courneya 2.1 Abstract 2.2 Introduction 2.2.1 Incidence of CRF 2.2.2 Etiology of CRF 2.2.3 Conceptual framework for the study of CRF 2.3 Assessment of CRF 2.3.1 Clinical syndrome of CRF 2.3.2 CRF-specific measurement instruments 2.4 Management strategies for CRF 2.4.1 Pharmacological interventions 2.4.2 Psychosocial interventions 2.4.3 Exercise interventions 2.4.3.1 Breast cancer 2.4.3.2 Prostate cancer 2.4.3.3 Hematopoietic stem cell transplantation 2.4.3.4 Advanced cancer 2.4.4.5 Combined interventions for CRF 2.5 Special considerations for exercise testing and programming 2.5.1 Screening for exercise participation 2.5.2 Exercise testing 2.5.3 Exercise programming 2.5.3.1 Prescription considerations for patients with poor functional capacity 2.5.3.2 Intermittent or interval exercise training 2.5.3.3 Muscular fitness training 2.5.3.4 The training index 2.5.3.5 Pacing 2.6 Summary and conclusions 2.7 References CHAPTER 3: Exercise as an intervention during breastcancer treatment Martina Markes 3.1 Abstrac 3.2 Introduction 3.2.1 Impact of breast cancer treatment 3.2.2 Physical activity behaviours 3.3 The evidence base for exercise: a systematic review 3.3.1 Methods of the systematic review 3.3.2 Description of studies 3.3.3 Effects 3.3.3.1 Physical and mental health 3.3.3.2 Adverse effects 3.3.4 Exercise adherence and maintenance 3.3.5 Quality of the evidence 3.3.6 Applicability of the evidence to the breast cancer population 3.3.7 Implications for research 3.4 Implementation and dissemination 3.5 Summary 3.6 References CHAPTER 4: Exercise after treatment for breast cancer: effects on quality of life Helen Crank and Amanda Daley 4.1 Abstract 4.2 Introduction 4.2.1 Incidence and survival from breast cancer 4.2.2 Consequences of breast cancer 4.2.3 Psychosocial and psychosocial interventions 4.3 The potential role of exercise after treatment for breast cancer 4.4 Chapter overview 4.5 Is exercise an effective quality of life intervention after treatment for breast cancer? Summary of the evidence 4.5.1 Setting the scene: early intervention studies 4.5.2 The 'boom' years 4.5.2.1 Trials of supervised aerobic exercise 4.5.2.2 Weight-training and resistance exercise interventions 4.5.2.3 Combined aerobic exercise and resistance training interventions 4.5.2.4 Pragmatic home-based exercise interventions 4.5.2.5 Alternative modes of exercise 4.5.2.6 Exercise versus other quality of life interventions 4.6 Reviews and meta-analyses 4.7 'What's it like?' Cancer survivor experiences of exercise 4.8 What next? 4.9 Summary and conclusions 4.10 References CHAPTER 5: