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Complexes de cuivre comme agents anticancéreux

Complexes de cuivre comme agents anticancéreux


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About the Book

Le succès du cisplatine a stimulé le développement de médicaments anticancéreux à base de métaux. Le cancer est sans aucun doute l'un des principaux problèmes de santé auxquels notre société est confrontée et l'une des principales cibles de la chimie médicinale. Bien que les complexes à base de platine aient été au centre de la recherche sur les agents chimiothérapeutiques, l'intérêt dans ce domaine s'est déplacé vers des agents autres que ceux à base de platine, afin de trouver des complexes métalliques différents ayant moins d'effets secondaires et une cytotoxicité similaire ou meilleure. Ainsi, une grande variété de complexes métalliques basés sur le titane, le gallium, le germanium, le palladium, l'or, le cobalt, le ruthénium et l'étain font l'objet d'études intensives pour remplacer le platine. En outre, les complexes à base de cuivre (II) semblent être des candidats très prometteurs pour la thérapie anticancéreuse; une idée soutenue par un nombre considérable d'articles de recherche décrivant la synthèse et les activités cytotoxiques de nombreux complexes de cuivre (II). Les ligands macrocycliques à base de Schiff basés sur la thiosémicarbazone et leurs complexes ont fait l'objet d'une attention considérable. En raison de leurs propriétés pharmacologiques, les bases de Schiff macrocycliques ont de nombreuses applications, par exemple comme antioxydant, antibactérien.


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Product Details
  • ISBN-13: 9786207856640
  • Publisher: KS Omniscriptum Publishing
  • Binding: Paperback
  • Language: French
  • Returnable: N
  • Weight: 154 gr
  • ISBN-10: 6207856643
  • Publisher Date: 22 Jul 2024
  • Height: 229 mm
  • No of Pages: 60
  • Spine Width: 4 mm
  • Width: 152 mm


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