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Biomarkers for Preclinical Alzheimer's Disease

Biomarkers for Preclinical Alzheimer's Disease


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International Edition


About the Book

Series Preface...

Preface...

Table of Contents...

Contributing Authors...

Part I Alzheimer's Disease as a Societal Challenge

1. Worldwide Economic Costs and Societal Burden of Dementia

Junfang Xu and Chengxuan Qiu


2. Epidemiology and Risk Factors of Alzheimer's Disease: A Focus on Diet

Cécilia Samieri


Part II Diagnostic Concepts

3. The Dimensional Structure of Subjective Cognitive Decline

Miguel A. Fernández-Blázquez, Marina Ávila-Villanueva, and Miguel Medina


4. Deriving and Testing the Validity of Cognitive-Reserve Candidates

Yaakov Stern and Christian Habeck


5. Methods for Pathological Classification of Alzheimer's Disease

Johannes Attems, Kirsty E. McAleese, and Lauren Walker


Part III Established Markers of Pathophysiology and Risk

6. Cerebrospinal Fluid Biomarkers of Preclinical Alzheimer's Disease

Panagiotis Alexopoulos and Chaido Sirinian


7. Brain Structural Imaging in Alzheimer's Disease

Sven Haller, Davide Zanchi, Cristelle Rodriguez, and Panteleimon Giannakopoulos


8. Brain Functional Imaging in Preclinical Alzheimer's Disease

Peter Häussermann, Thorsten Bartsch, and Oliver Granert


9. Imaging of Brain Amyloid Load in Early Alzheimer's Disease

Timo Grimmer and Jennifer Grace Perryman


10. Functional EEG Connectivity Alterations in Alzheimer's Disease

Florian Hatz and Peter Fuhr


Part IV Biomarker Discovery

11. A Selected Reaction Monitoring Protocol for the Measurement of sTREM2 in Cerebrospinal Fluid

Amanda J. Heslegrave, Wendy E. Heywood, Kevin M. Mills, Henrik Zetterberg


12. Soluble Amyloid Precursor Proteins in Blood: Methods and Challenges

Robert Perneczky and Panagiotis Alexopoulos


13. Tau Imaging in Preclinical Alzheimer's Disease

Paul Edison


14. Retinal Imaging in Early Alzheimer's Disease

Tom MacGillivray, Sarah McGrory, Tom Pearson, and James Cameron


15. In Vivo Volumetry of the Cholinergic Basal Forebrain

Michel J. Grothe, Ingo Kilimann, Lea Grinberg, Helmut Heinsen, and Stefan Teipel


Part V Patient Benefit and Ethical Considerations

16. Clinical Meaningfulness of Biomarkers Endpoints in Alzheimer's Disease Research

Kok Pin Ng, Tharick A. Pascoal, Xiaofeng Li, Pedro Rosa-Neto, and Serge Gauthier


17. The Ethics of Biomarker-Based Preclinical Diagnosis of Alzheimer's Disease

Alexander F. Kurz and Nicola T. Lautenschlager


18. Shared Decision-Making and Important Medical and Social Decisions in the Context of Early Diagnosis of Alzheimer's Disease

Katharina Bronner and Johannes Hamann



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Product Details
  • ISBN-13: 9781493976737
  • Publisher: Humana Press
  • Publisher Imprint: Humana Press
  • Edition: 1st ed. 2018
  • Language: English
  • Returnable: Y
  • Spine Width: 18 mm
  • Width: 178 mm
  • ISBN-10: 1493976737
  • Publisher Date: 27 Feb 2018
  • Binding: Hardback
  • Height: 254 mm
  • No of Pages: 272
  • Series Title: Neuromethods
  • Weight: 766 gr


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