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Binding, Transport and Storage of Metal Ions in Biological Cells

Binding, Transport and Storage of Metal Ions in Biological Cells


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About the Book

The chemistry of metals is associated with many health matters, from its role in diseases such as neurodegeneration, cancer and diabetes and the toxicological effects of non-essential metal ions such as cadmium and arsenic, to its uses in therapeutic and diagnostic applications. This book focuses on the molecular aspects of the ingress, transport, regulation and egress of both essential and non-essential metal ions emphasising that chemistry controls the crucial nutrient and toxicological properties. Structured around the periodic table, each chapter is written by a leading expert and documents a different element and its structural, chemical and biochemical role in biological cells giving a logical structure for the comparison of properties. This is the first book to combine the molecular features of metal ions in nutrition, toxicology and pharmacology at the research front level for students, postgraduates and researchers in academic and industry.
About the Author:

Wolfgang Maret FRSC obtained his MSc (chemistry) and PhD (natural sciences) from Saarland University, Saarbrücken, Germany.After postdoctoral research at the University of Chicago (Department of Biophysics and Theoretical Biology), his first faculty appointment was at Harvard Medical School.In 2002, he joined the University of Texas Medical Branch in Galveston, Texas as an Associate Professor.He is now a Professor of Metallomics at King's College London, London, UK.His research interests began with the catalytic mechanisms of metalloenzymes as investigated with spectroscopic and kinetic methods and continued with the role of metal ions in health and disease, the molecular mechanisms of how proteins control metal ions, and the cellular mechanism of how metal ions control protein structure and function.

Anthony G Wedd is Tasmanian by birth and holds both PhD and DSc from the University of Tasmania.He spent a postdoctoral period with Professor Joseph Chatt (University of Sussex) before becoming a staff member at La Trobe University in Melbourne, Australia.He transferred to the University of Melbourne in 1991 as a Professor of Chemistry. His long term interests have been in polyoxometalate cluster chemistry and in biological inorganic chemistry, and particularly the relevant chemistries of molybdenum, tungsten and copper.


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Product Details
  • ISBN-13: 9781849735995
  • Publisher: Royal Society of Chemistry
  • Publisher Imprint: Royal Society of Chemistry
  • Depth: 51
  • Language: English
  • Returnable: Y
  • Spine Width: 52 mm
  • Weight: 1595 gr
  • ISBN-10: 1849735999
  • Publisher Date: 28 Jul 2014
  • Binding: Hardback
  • Height: 240 mm
  • No of Pages: 938
  • Series Title: Metallobiology
  • Sub Title: Rsc
  • Width: 164 mm


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