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Applications of Mass Spectrometry in Microbiology

Applications of Mass Spectrometry in Microbiology


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International Edition


About the Book

Introduction.- SECTION I. METHODOLOGY AND TECHNIQUES.- Methods and instrumentation in mass spectrometry for the differentiation of closely related microorganisms.- Sample preparation methods for the rapid MS analysis of microorganisms.- Advantages offered by proteomic strategies for rapid biodetection.- Bottom Up Proteomics Methods for Strain-Level Typing and Identification of Bacteria.- Maximizing the taxonomic resolution of MALDI-TOF-MS-based approaches to bacterial characterization: From culture conditions through data analysis.- SECTION II. SUB-SPECIES DISCRIMINATION.-

Modulation of the Discriminatory Power of MALDI-TOF MS Profiling for Distinguishing between Closely Related Bacterial Strains.- Discriminatory Power of MALDI-TOF Mass Spectrometry for Phylogenetically Closely Related Microbial Strains.- MALDI-TOF MS as a novel tool for dereplication and characterization of microbiota in bacterial diversity studies.- Bacterial Identification at the Serovar level by Top-down Mass Spectrometry.- SECTION III. DRUG RESISTANCE MONITORING AND ASSAYS.- Rapid profiling of human pathogenic bacteria and antibiotic resistance employing specific tryptic peptides as biomarkers.- Detection of β-lactamases and their activity using MALDI-TOF MS.- Stable-isotope based strategies for rapid determination of drug resistance by mass spectrometry.


About the Author: Plamen A. Demirev, Johns Hopkins University Applied Physics Laboratory
Todd Sandrin, School of Mathematical and Natural Sciences, Arizona State University


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Product Details
  • ISBN-13: 9783319260686
  • Publisher: Springer
  • Publisher Imprint: Springer
  • Edition: 1st ed. 2016
  • Language: English
  • Returnable: Y
  • Spine Width: 21 mm
  • Weight: 711 gr
  • ISBN-10: 3319260685
  • Publisher Date: 19 Jan 2016
  • Binding: Hardback
  • Height: 234 mm
  • No of Pages: 336
  • Series Title: English
  • Sub Title: From Strain Characterization to Rapid Screening for Antibiotic Resistance
  • Width: 156 mm


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