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Lebererkrankungen und Diabetes mellitus

Lebererkrankungen und Diabetes mellitus


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About the Book

Diabetes mellitus (DM) ist eine Störung der Bauchspeicheldrüse mit verminderter Insulinausschüttung oder Resistenz des peripheren Gewebes gegen Insulin, die entweder als Typ 1, der fünf bis zehn Prozent der DM-Fälle ausmacht, oder als Typ 2 (TYP 2), der neunzig bis fünfundneunzig Prozent der DM-Patienten ausmacht, klassifiziert wird. Die Komplikationen bei DM-Patienten können sich auf mehrere lebenswichtige Organsysteme auswirken und zu ernsten pathologischen Zuständen wie der nichtalkoholischen Fettlebererkrankung (NAFLD) führen. Zirrhose (Fibrose): Sie führt zu einer Schwächung der Insulinausscheidung durch die Hepatozyten und ist außerdem mit erhöhten Konzentrationen von Endprodukten der fortgeschrittenen Glykierung verbunden, bei denen die Glukose kovalente Addukte mit den Proteinen im Plasma über einen nicht-enzymatischen Vorgang bildet, der als Glykierung bekannt ist. Beim hepatozellulären Karzinom (HCC) sind Hyperinsulinämie, chronische Entzündungen und IR mit DM verbunden und stehen alle in Zusammenhang mit bösartigen Tumoren. Das erhöhte DM-Risiko bei HBV-Patienten im Gegensatz zu nicht HBV-infizierten Personen ist bestätigt. Akutes Leberversagen (ALF): In neueren Arbeiten wurde ein Leberversagen bei DM-Patienten festgestellt, das mit der Einnahme von Troglitazon in Verbindung gebracht wird, das den Blutzuckerspiegel senkt.


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Product Details
  • ISBN-13: 9786205931608
  • Publisher: KS Omniscriptum Publishing
  • Publisher Imprint: Verlag Unser Wissen
  • Height: 229 mm
  • No of Pages: 60
  • Spine Width: 4 mm
  • Width: 152 mm
  • ISBN-10: 6205931605
  • Publisher Date: 25 Apr 2023
  • Binding: Paperback
  • Language: German
  • Returnable: N
  • Weight: 154 gr


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